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Experience of therapy of the first episode of schizophrenia paliperidony palmitate (casereport)

N.M. Bakunovich, E.Yu. Antokhin, R.I. Palaeva, E.M. Kryukova, S.V.Palyaeva

Orenburg state medical university
Orenburg regional clinical insane hospital No. 1, Russia

Summary
The clinical case of the patient with the first psychotic episode is provided to publications. Aspects of the medicinal pathomorphism of schizophrenia which led to the protragirovanny initial period of a disease are sorted. Therapy risperidony and paroksetiny did not lead to a due reduction of sensual crazy experiences. Change of a risperidon with injections of a paliperidon of palmitate promoted forming of stable remission and restoration of social functioning. Keywords: clinical case, paliperidon palmitate, the first episode of schizophrenia

Контакт: antioh73@yandex.ru

References: 

1. Fusar-Poli P., Oliver D. etc. RealWorldImplementation of a TransdiagnosticRiskCalculatorfortheAutomaticDetection of individualsatrisk of psychosisinclinicalroutine: studyprotocol. // FrontiersinPsychiatry. – 2019. - V. 10, article 109. - https://doi.org/10.3389/fpsyt.2019.00109
2. Neznanov N.G., Shmukler A.B., Kostyuk G.P., Sofronov A.G. i soavt. Pervyipsikhoticheskiiepizod: epidemiologicheskieaspektyorganizatsiipomoshchi //Sotsial'naya i klinicheskayapsikhiatriya. – 2018. – T. 28, № 3. – S. 5–11.
3. GurovichI.Ya., Shmukler A.B., Lyubov E.B. Klinikapervogopsikhoticheskogoepizoda (dnevnoistatsionariliotdelenie s rezhimomdnevnogostatsionara, profilirovannyedlyapomoshchibol'nym s pervymepizodomshizofrenii): metodich. rekomendatsii. – M., 2003.
4. Robinson D., Woerner M.G., Alvir J.M. etal. Predictors of relapsefollowingresponsefrom a firstepisode of schizophreniaorschizoaffectivedisorder // ArchGenPsychiatry. – 1999. – Vol. 56, No. 3. – P. 241–247.
5. AntokhinE.Yu., Budza V.G., Kryukova E.M., Palaeva R.I.
Psikhopatologiyadepressiinapostpristupnometapetecheniyapervogoepizodashizofrenii: organizatsiyapomoshchipatsientam v otdeleniipervogopsikhoticheskogoepizoda, ponyatiedissotsiirovannoipostpristupnoidepressii//
Psikhiatriya i psikhofarmakoterapiya. - 2017. - T. 19. № 4. - S. 4-11.
6. Dmitrieva E.G., Semke A.V., Bokhan N.A., Dubrovskaya V.V. Osobennostiadaptatsiibol'nykhshizofrenieiprirannemvyyavlenii i korrektsiiriskanesoblyudeniyaterapii. //Sovremennayaterapiyapsikhicheskikhrasstroistv. – 2018. - № 3. – S. 11-17.
7. AntokhinE.Yu. Osobennostikognitivnykh i sotsial'nykhdisfunktsii u bol'nykhshizofreniei s pervympsikhoticheskimepizodom i podkhody k ikhkorrektsii//
VestnikSankt-Peterburgskogouniversiteta. Meditsina. - 2011. - № 1. - S. 71-80.
8. AntokhinE.Yu., Budza V.G., Gorbunova M.V., Kryukova E.M. Sravnitel'nyiopytispol'zovaniyaatipichnykhantipsikhotikov v klinikepervogoepizoda// Ural'skiimeditsinskiizhurnal. - 2007. - № 4. - S. 97-101.
9. Lyubov E.B., Chapurin S.A., ChurilinYu.Yu. i gruppaissledovatelei. Kliniko-sotsial'naya i ekonomicheskayarezul'tativnost' paliperidonapal'mitata u bol'nykh s pervymepizodomshizofrenii // Sotsial'naya i klinicheskayapsikhiatriya. 2019. - T.29. №1. - S.60-72.
10. Lyubov E.B., AntokhinE.Yu., Bychkova O.G. i soavt. Statsionarnyepatsienty o svoikhpotrebnostyakh i udovletvorennostipsikhiatricheskoipomoshch'yu//
Nezavisimyipsikhiatricheskiizhurnal. - 2012. - № 2. - S. 28-32.
11. Lyubov E.B., AntokhinE.Yu., Shlafer A.M. i soavt. Otsenkabol'nichnymipatsientamisvoikhpotrebnostei i udovletvorennostipsikhiatricheskoipomoshch'yu// Sotsial'naya i klinicheskayapsikhiatriya. - 2012. - T.22. №4. - S.51-56.
12. Budza V.G., AntokhinE.Yu., Golenishchenko A.V. i soavt. Nekotoryefaktory, opredelyayushchiestanovleniekomplaensa v psikhiatrii // Psikhicheskoezdorov'e. – 2013. – T. 11. № 9 (88). – S. 26–36.
13. AntokhinE.Yu., Budza V.G., Kryukova E., Lazareva N.E.
Thestructure of thepsychologicaladaptationinschizophreniapatientswiththefirstpsychoticepisode //EuropeanPsychiatry. - 2010. - T. 25. № S1. - S. 1144.
14. AntokhinE.Yu. Protectpsychologicalmechanisms of postpsychoticdepressioninpatientsatfirstepisode of schizophrenia //Ceska a SlovenskaPsychiatrie. - 2012. - T. 108. № 1. - S. 217-218
15. Grigor'eva E.V. Sotsial'noefunktsionirovanie i kachestvozhiznibol'nykhshizofreniei: fokusnapaliperidonapal'mitat (klinicheskiisluchai) // Obozreniepsikhiatrii i meditsinskoipsikhologiiimeni V.M. Bekhtereva. – 2017. – № 1. – S. 59–62.
16. AntokhinE.Yu., Budza V.G., Kryukova E.M., Palaeva R.I.
Postpristupnayadepressiyapripervomepizodeshizofrenii: issledovanieperfektsionizma // Sotsial'naya i klinicheskayapsikhiatriya. - 2017. - T. 27. № 4. - S. 38-46.
17. AntokhinE.Yu., Budza V.G., Kryukova E.M., Palaeva R.I. Dissotsiirovannayapostpristupnayadepressiyapripervomepizodeshizofrenii: issledovaniesamostigmatizatsii // Sotsial'naya i klinicheskayapsikhiatriya. - 2019. - T.29. №1. - S.17-23.
18. DrobizhevM.Yu., Kalinina E.V., AntokhinE.Yu., SorokinaE.Yu. Praktikaprimeneniyaantipsikhotikov i korrektorov v psikhiatrii. Pervyerezul'tatyprogrammy ANKORPSI (antipsikhotiki i korrektory v psikhiatrii) // Sotsial'naya i klinicheskayapsikhiatriya. – 2015. – T. 25, № 2. – S. 65–77
19. Sramer J.A., Rosenheck R. Sompliancewithmedicationregimensformental and physicaldisorders // PsychiatricServ. – 1998. – N. 49. – P. 196–201.
20. Oehl M., Hummer M., Fleischhacker W. Sompliancewithantipsychotictreatment // ActaPsychiatrScand. – 2000. – No. 102. – P. 83–86.
21. Daghistani N., Rey J.A. InvegaTrinza: Thefirstfour-Times-a-Year, Long-ActingInjectableAntipsychoticAgent // P T – 2016. – Vol. 41 (4). – P. 222–227.
22. Weiden P.J., Zygmunt A. Theroadback: workingwiththeseverelymentallyill // Medicationnoncomplianceinschizophrenia: part 1. Assessment // J PractPsychiatryBehavHealth. – 1997. – P. 106–110.
23. Mosolov S.N., Tsukarzi E.E., Kapiletti S.G. Antipsikhoticheskayafarmakoterapiyashizofrenii: otnauchnykhdannykh k klinicheskimrekomendatsiyam // Mosolov S.N. Biologicheskiemetodyterapiipsikhicheskikhrasstroistv. Dokazatel'nayameditsina – klinicheskoipraktike. Moskva. – 2012. – S. 11–61
24. Olanguji A. T., Clark S. R., Baune B. T. Long-actingatypicalantipsychoticsinschizophrenia: A systematicreview and meta-analyses of effectsonfunctionaloutcome // Aust N Z J Psychiatry. – 2019. - Apr 8:4867419837358. -https://doi.org/ 10.1177/0004867419837358.
25. AntokhinE.Yu., Budza V.G., Belova O.S., Palyaeva S.V., Kryukova E.M.
Paliperidon (invega) v terapiishizoaffektivnogopsikhoza u podrostka (klinicheskiisluchai) // Sovremennayaterapiyapsikhicheskikhrasstroistv. 2018. № 3. S. 45-48.
26. Bekker R.A., BykovYu.V. Prolongirovannyeantipsikhotikikompanii «Yanssen» v istoricheskomrazreze: proshloe, nastoyashchee, budushchee // Psikhiatriya i psikhofarmakoterapiyaimeni P.B. Gannushkina. – 2017. – № 6. – S. 18–27
27. Awouters F.H., Lewi P.J. Fortyyears of antipsychoticdrugresearch – fromhaloperidoltopaliperidone – withDr. PaulJanssen // ArzneimittelforSchung. – 2007. – No. 57 (10). – S. 625–632
28. Stahl S.M., Muntner N. Stahl’sessentialpsychopharmacology: neuroscientificbasis and practicalapplications. – 4th ed. – CambridgeUniversityPress, 2013.
29. Pandina G.J., Lindenmayer J.P., Lull J. etal. a randomized, placebo-controlledstudytoassesstheefficacy and safety of 3 doses of paliperidonepalmitateinadultswithacutelyexacerbatedschizophrenia // J clinPsychopharmacol. – 2010. – Vol. 30 (3). – P. 235–244
30. RetyunskiiK.Yu. Osobennostifarmakokinetikipaliperidona i egoprolongirovannoiin"ektsionnoiformypaliperidonapal'mitata // Sovremennayaterapiyapsikhicheskikhrasstroistv. – 2012. – № 2. – S. 25–32.
31. Oleneva E.V., Kapiletti S.G., Ryvkin P.V., LadyzhenskiiM.Ya. Rispoleptkonsta – 10 letprimeneniya v Rossii: nekotoryeitogi // Sovremennayaterapiyapsikhicheskikhrasstroistv. – 2015. – № 1. – S. 10–24.
32. KozlovYa.S., AntokhinE.Yu., Budza V.G., Kryukova E.M., Palyaeva S.V. Paliperidonapal'mitat v terapiipervogoepizodaparanoidnoishizofrenii (klinicheskiisluchai) // Sovremennayaterapiyapsikhicheskikhrasstroistv. - 2018. - № 2. - S. 35-40.