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Intramuscular Ziprasidone: experience and potential for use in psychiatry

V.E. Medvedev 1, T.S. Syunyakov 2
1RUDN University; 2 Pfizer LLC

Summary: This review represents data on efficacy of intramuscular ziprasidone in treatment of acute agitation due to different psychiatric disorders (schizophrenia, BAR, schizoaffective disorder, alcohol and other types of intoxication) including cases of other intramuscular antipsychotics inefficacy. Poverty of side effects and similar efficacy in different age groups suggest that intramuscular ziprasidone may be effective in treatment of acute agitation in children, adolescent and geriatric patients including those with somatic disorders. Elaborated strategies for switching from intramuscular to oral ziprasidone provide pharmacological continuity without losing the treatment efficacy.